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11202 自然科學
創新生命科學研究方法〡Offered in English❤️0502微調中❤️
王慧菁 / 廖品超 / 陳韋靜 / 周雅菁 / 林郁婷 / 李以如 / 林珮君 / 謝琬甄 教授

本課程主要講授發表在Nature Methods期刊中的新興醫學及生命科學研究方法,並探討這些技術的未來應用。 

課程簡述
Brief course description
本課程主要講授發表在Nature Methods期刊中的新興醫學及生命科學研究方法,並探討這些技術的未來應用。
This lecture will be given in English. 

The lectures will focus on introducing select key methodologies published in the prestigious journal Nature Methods, as well as discussing their potential future implications. The teachers will introduce 17 different method topics and the lecture will be given in a hybrid mode (physical + online).  
 
 
 
課程說明
Course Description
Nature Methods is a monthly journal publishing novel methods and significant improvements to basic life sciences research techniques. The journal is aimed at a broad, interdisciplinary audience of academic and industry researchers actively involved in laboratory practice. It provides researchers with new tools to conduct their research and places a strong emphasis on immediate practical relevance and potential to advance new biological applications.

We noted that each paper published in Nature Methods must be accompanied by strong validation, an application to an important biological question and results illustrating its performance in comparison to available approaches. Thus, papers are selected for publication based on broad interest, thorough assessments of methodological performance and comprehensive technical descriptions that facilitate immediate application. Accordingly, we believe our students may benefit a lot by learning these new methods.


指定用書
Textbook Book
Nature methods 
  The electronic international standard serial number (EISSN) is 15487105. 
  https://www.nature.com/nmeth/ 
  https://www.nature.com/nmeth/articles?type=method-to-watch 
 
   

教學方式
Teaching Method
Each lecture will consist of two parts. The first part will feature lectures given by individual teachers, while the second part will involve student presentations and discussions guided by the teachers 
 

 
教學進度
Course Content 
Please see the following table.
 Week  Date  Teacher  Topic 
 1  09/14   Lily Wang  General lecture introduction  
      Topic-1: Method to watch 2022: Imaging without the labels https://www.nature.com/articles/s41592-02101376-0
Topic-2: Organic dyes for live imaging https://www.nature.com/articles/s41592-020-01032-z 

 2  09/21  Wei-Ching Chen Topic-3: Method to watch 2020: Tools for metabolomics http:://www.nature.com/articles/s41592-019-0710-6 
      Topic-4: Method to watch 2023: Annotating unknown metabolites http://www.nature.com/articles/s41592-022-01735-5 

 3  09/28  Teacher’s  day
 4  10/05   Pei-Chun Lin Topic-5: ClampFISH Nat Methods 19, 1403–1410 (2022). https://doi.org/10.1038/s41592-022-01653-6 
      Student presentation 

 5  10/12   Ya-Ching Chou Topic-6: Joint profiling of DNA methylation and chromatin architecture in single cells
https://www.nature.com/articles/s41592-0190502-z 
      Student presentation

 6  10/19  I-Ju Lee  Topic-7: Next-Generation Expansion Microscopy https://www.nature.com/articles/s41592-023-01793-3 and related articles
      Student presentation
 
7   10/26  Yu-Ting Lin Topic-8: Controlling cellular activities with light Nat Methods 20, 357–358 (2023)
https://www.nature.com/articles/s41592-022-01745-3 
      Student presentation 

8  11/02   Pei-Chun Lin Topic-9: Cryo-electron tomography Nat Methods (2023). https://doi.org/10.1038/s41592023-01783-5 
      Student presentation
 
9  11/09   I-Ju Lee  Topic-10: Methods to watch 2023: A light switch for targeted genomics
https://www.nature.com/articles/s41592-022-01733-7 
       Student presentation 

10  11/16  Ya-Ching Chou  Topic-11: SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
https://www.nature.com/articles/s41592-021-01255-8
      Student presentation

11   11/23  Lily Wang Topic-12: Neuroscience goes viral
https://www.nature.com/articles/s41592-021-01373-3 
      Student presentation

12   11/30   Wan-Chen Hsieh  Topic-13:T cell development in a dish Nature Methods volume 18, page35 (2021)
https://www.nature.com/articles/s41592-020-01047-6 
      Student presentation 

13  12/07  Yu-Ting Lin  Topic-14: Patch-seq technique Nat Methods 19, 1340–1344 (2022) https://www.nature.com/articles/s41592-022-01662-5 
      Student presentation 

14  12/14  Wan-Chen Hsieh Topic-15:Macrophages enter CAR immunotherapy Nature Methods volume 17, page 561 (2020)
https://www.nature.com/articles/s41592-020-0862-4
      Student presentation

15  12/21  Pin-Chao Liao Topic-16:Automated segmentation and tracking of mitochondria in live-cell time-lapse images Nature Methods volume 18, pages 1091–1102 (2021)
https://www.nature.com/articles/s41592-021-01234-z
 
      Student presentation 

 
16  12/28  Pin-Chao Liao Topic-17: Actin chromobody imaging reveals suborganellar actin dynamics Nature Methods volume 17, pages 917–921 (2020) https://www.nature.com/articles/s41592-020-0926-5 
      Student presentation 


成績參考 
♠ Course participation: 20%
♠ Presentation: 80% (40% classmates, 40% teacher) 

 
相關網頁
 https://www.nature.com/nmeth/ 
♠ https://www.nature.com/nmeth/articles?type=method-to-watch 
 

 

瀏覽人次:577
11001 自然科學
當代認知神經科學:腦與心智〡自錄版2
焦傳金 教授

認知神經科學是一門新興的研究領域,主要是探索腦與心智的關連 性。從感覺與知覺、學習與記憶、注意力與情緒、同理與厭惡、決策與執行、乃至意識的產生,都是認知神經科學的範疇......

 

課程簡述 
 Course description
         認知神經科學(Cognitive Neuroscience)是一門新興 的研究領域,主要是探索腦與心智(Brain and Mind)的關連性。從感覺與知 覺(Sensation and Perception)、學習與記憶(Learning and Memory)、注 意力與情緒(Attention and Emotion)、同理與厭惡(Empathy and Disguise)、決策與執行(Decision-making and Execution)、乃至意識 (Consciousness)的產生,都是認知神經科學的範疇。瞭解這些認知行為背 後的神經科學不僅是本世紀最重要的一項科學探索,也與每個人的有密切的關 係。例如:神經經濟學(Neuroeconomics)與消費者行為及市場調查有關, 退化性神經疾病(Neurodegenerative disorders)與老年失智症有關。在本 課程中,我們將依序探討認知神經科學中的主要課題,重點在於介紹最新的研 究發展,並討論這些科學發現對個人及社會的衝擊。本課程將以科學人雜誌過 去所發表有關認知神經科學的文章為主,並以影片及期刊論文為輔,搭配課程 中互動討論,使無心理學或生物學背景的學生亦可學習此一課程。

 

 

參考用書
 Reference

 Cognitive Neuroscience: The Biology of the Mind (Fourth Edition),

Michael Gazzaniga, Richard B. Ivry, George R. Mangun (2013)
 

 

教學進度
Course schedule  

Week Topic                  Note
Week 1 腦與心智簡介
  簡介各週內容,暴力行為在腦中的運作模式 第一周上課使用直播方式,不需前往教室 
Week 2 感覺&知覺 I
  視覺的錯視、視覺訊息的處理
Week 3 感覺&知覺 II
  奧妙的色彩如何影響大腦認
Week 4 感覺&知覺 I II
  原來我們聽到的可能不一樣、基因影響嗅覺辨識!
Week 5 學習&記憶 
  感官、短期、長期,原來有不同的記憶形式
Week 6 睡眠&夢
  我可以都不睡覺嗎? 我為何需要睡覺?
Week 7 報償&成癮
  為何毒品這麼難戒除,成癮對腦造成的傷害
Week 8 溝通&語言
  動物們如何溝通,為何電子書無法取代紙本?
Week 9 理性&感性
  動物也會難過,不同情緒由不同腦區控制
Week 10 全校運動會 選擇&決策 
  如何做出選擇,究竟你在選什麼?
Week 11 同理心
  網路和面對面的霸凌有何不同,你懂我的痛嗎?
Week 12 智力&創造力
  天才從何而來? 創意如何產生?
Week13 發育&可塑性
  嬰兒天生會做哪些事?學前教育可以如何進行
Week 14 老化&疾病
  如何優雅的老化,能阻止大腦變老嗎? 
Week 15 腦科學&科技&社會
  男、女頭腦大不同?
Week 16 意識&自由意志
  植物人有意識嗎?
Week 17 期末考週
  繳交期末報告
   

 

 

溫馨小提醒
 Warm reminder

本課程同時採用實體上課與同步遠距教學
本課程會開放高中生參與,有機會與高中生合作期末報告
Grading policy

課堂參與:40% (每堂課結束後需將課程心得與自我經驗分享上傳至社群軟體 fb、ig)

課堂小考:30%  (每個段落皆有課堂小考,以 slido 進行)

期末報告:30%  (製作一個與課程相關的影片,並附上書面報告)

課前後總結問卷(加分):0-10% 
課程要求

1.攜帶行動載具(手機、平版、筆電)來上課  

2.下載 slido

3.擁有任一社群軟體   
    
 
加簽規定 

1.欲加簽者請參與第一堂線上直播課程,並於課程中填寫加簽表單,
   將依據人數抽籤,表單關閉後不再開放加簽
       

2.大一新生欲加簽者同樣需於 9/15(三)第一堂課參與線上直播課

3.直播連結: https://youtu.be/PzcXgcReoWs
    
 

 劉璦瑜_當代生命科學腦與心智 week1_week10筆記分享!

瀏覽人次:59744
10902 自然科學
複變數函數論
程守慶 教授
This course will cover the concept of holomorphic functions, Cauchy's integral formula. Maximum modulus principle for holomorphic functions shall be proved....
 
  
課程說明
Course Description

Basically we shall cover the following topics.
(1) Cauchy-Riemann equation,Cauchy theorem for holomorphic functions,
(2) Cauchy integral formula,
(3) Maximum modulus Principle,
(4) Laurent series,meromorphic functions,
(5) Calculus of residues,
(6) Harmonic functions of two real variables,
(7) Conformal mappings, Riemann mapping theorem.
   
  
 

指定用書
Text Books 
  
 
 
參考書籍
 References
1 L. V. Ahlfors: Complex Analysis,
2 E. M. Stein and R. Shakarchi: Complex Analysis, Princeton University Press.
3.

John Wiley & Sons, INC.
4. W. Rudin: Real and Complex Analysis, McGraw-Hill Book Company.
   
 
 
教學方式
 Teaching Method 
Lecture and assignments.
 
 
成績考核
 Evaluation  
It will be announced in the first class.

 

 

 
 

 

瀏覽人次:210207
10901 自然科學
當代認知神經科學:腦與心智〡自錄版1
焦傳金 教授

認知神經科學(Cognitive Neuroscience)是一門新興的研究領域,主要是探索腦與心智的關連 性。從感覺與知覺、學習與記憶、注意力與情緒 、同理與厭惡、決策與執行、乃至意識的產生,都是認知神經科學的範疇。Cognitive Neuroscience is an emerging academic field concerned with the relation of Brain and Mind. Topics such as: sensation and perception, learning and memory, attention and emotion, empathy and disguise, decision-making and execution, and consciousness, all belong to the field of Cognitive Neuroscience.

 


課程簡述 
        Brief course description

        認知神經科學(Cognitive Neuroscience)是一門新興的研究領域,主要是探索腦與心智(Brain and Mind)的關連性。從感覺與知覺(Sensation and Perception)、學習與記憶(Learning and Memory)、注意力與情緒 (Attention and Emotion)、同理與厭惡(Empathy and Disguise)、決策與執行(Decision-making and Execution)、乃至意識(Consciousness)的產生,都是認知神經科學的範疇。瞭解這些認知行為背後的神經科學不僅是本世紀最重要的一項科學探索,也與每個人的有密切的關係。例如:神經經濟學(Neuroeconomics)與消費者行為 及市場調查有關,退化性神經疾病(Neurodegenerative disorders)與老年失智症有關。
        在本課程中,我們將依序探討認知神經科學中的主要課題,重點在於介紹最新的研究發展,並討論這些科學發現對個人及社會的衝擊。本課程將以 科學人雜誌過去所發表有關認知神經科學的文章為主,並以影片及期刊論文為輔,使無心理學或生物學背景的學生亦可學習此一課程。

Cognitive Neuroscience is an emerging academic field concerned with the relation of Brain and Mind. Topics such as: sensation and perception, learning and memory, attention and emotion, empathy and disguise, decision-making and execution, and consciousness, all belong to the field of Cognitive Neuroscience.Understanding the neuroscience behind these cognitive behaviors not only marks one of the most significant science discovery in this century but also deeply connects to individual’s daily life. For example, Neuroeconomics involves in consumer behavior and market research; Neurodegenerative disorders is related to Alzheimer's disease.
In this course we’ll introduce some main topics of Neuroscience in order, focusing on the latest research and development, and we’ll discuss the influence on society and individuals from these discoveries. Most of the learning materials come from articles about Cognitive Neuroscience on Scientific American of these years, supplied with films and periodical literature as auxiliaries, so students without psychology or biology background can also participate in this course. 

  

教學進度
         Course schedule 

Week Topic   Note
Week 1 ♦ 與心智簡介 簡介各週內容,暴力行為在腦中的運作模式
  Introduction to Brain and Mind –
To introduce the whole course and the operation modes of violence in brains
Week 2 ♦感覺&知覺 I 視覺的錯視、視覺訊息的處理
  Sensation and Perception I – Optical illusion & the Operation of Visual Signals
 Week 3 ♦感覺&知覺 II 奧妙的色彩如何影響大腦認知
  Sensation and Perception II – How do the colors affect our perception?
Week 4 ♦感覺&知覺 III 原來我們聽到的可能不一樣、基因影響嗅覺辨識!
  Sensation and Perception III – 
What we hear may be different & Genes determine our olfactory sensation 
Week 5 ♦學習&記憶 感官、短期、長期,原來有不同的記憶形式
  Learning and Memory – Different memory modes
Week 6 ♦睡眠&夢 我可以都不睡覺嗎? 我為何需要睡覺?
  Sleep and Dreams – Why we need to sleep?
Week 7 ♦報償&成癮 為何毒品這麼難戒除,成癮對腦造成的傷害
  Reward and Addiction – Why is it so hard to quit drugs & how do drugs harm the brains
Week 8 ♦溝通&語言 動物們如何溝通,為何電子書無法取代紙本?
  Communication and Language – The ways animals 
Week 9 ♠♠♠ 全  校  運  動  會  停  課  YA! ♠♠♠
                         Taking a day off – NTHU sports day

Week 10 ♦理性&感性 動物也會難過,不同情緒由不同腦區控制
   Rationality and Sensibility – Emotions are controlled by different parts of the brain
Week 11 ♦選擇&決策 如何做出選擇,究竟你在選什麼?
  Choice and Decision-making – How to make choices?
Week 12 ♦同理心 網路和面對面的霸凌有何不同,你懂我的痛嗎?
  Empathy – The difference between cyberbullying and face-to-face bullying & Can others understand my pains?
Week 13 ♦智力&創造力 天才從何而來? 創意如何產生?
  Intelligence and Creativity – Where does genius come from?
& How does creativity be formed?
Week 14 ♦發育&可塑性 嬰兒天生會做哪些事?學前教育可以如何進行
  Development and Plasticity – What can infants do by nature? & Preschool education
Week 15 ♦老化&疾病 如何優雅的老化,能阻止大腦變老嗎?
  Aging and Disease – How can we age elegantly?& Is it possible to prevent the brains from aging?
Week 16 ♦腦科學&科技&社會 男、女頭腦大不同?
  Brain Science, Technology and Society –The difference between female brains and male brains
Week 17 意識&自由意志 植物人有意識嗎?
  Consciousness and Free Will – Do vegetative people contain their free will?
Week 18 期末考週 繳交期末報告 
  The week of final exam - Hand in the final project
   
   

 

 溫馨小提醒  

        Warm reminder
♠ 本課程同時採用實體上課與同步遠距教學 
  This course is lectured in the classroom as well as through distance learning!

Grading policy:

課堂參與:40% (每堂課結束後需將課程心得與自我經驗分享上傳至社群軟體 fb、ig)
Class attendance:40% (Sharing your experience and thoughts of the course on your fb or ig) 

課堂小考:30%  (每個段落皆有課堂小考,以 slido 進行)
Quizzes:30% (There are quizzes for each parts, performed with slido)

期末報告:30% (一份 3 頁 A4 的課程主題延伸報告)
Final project : 30%

課前後總結問卷(加分):5%
Questionnaire ( bonus ) : 5%
 
課程要求

1.攜帶行動載具(手機、平版、筆電)來上課
    Bring your mobile devices (smartphone, tablet, or laptop) to class

2.下載 slido
     Download slido app

3.擁有任一社群軟體
    Having a social media account
 


 

瀏覽人次:228852
10802 自然科學
系統神經科學
焦傳金 教授

腦科學為21世紀最重要的研究領域,而神經科學即是腦科學的基礎。在本課程中,我們將介紹神經網絡的結構與功能,這是介於細胞神經科學與認知神經科學的重要基礎課程。

  

課程概述
          Course Description

         腦科學為21世紀最重要的研究領域,而神經科學即是腦科學的基礎。在本課程中,我們將介紹神經網絡的結構與功能,這是介於細胞神經科學與認知神經科學的重要基礎課程。本課程內容特別專注於探討感覺神經系統與運動神經系統。藉由重要觀念的解說與實驗數據的分析,本課程期望所有修習的學生都能瞭解神經系統運作方式的基本法則。
         Brain science is the most important research area in 21st century and cellular neuroscience is the basis of brain science. In this course, we are going to introduce the structures and functions of neural network which is a basic but important course in between cellular neuroscience and cognitive neuroscience. This course will be specifically focusing on the sensory nervous system and motor nervous system. With the explanation of important concepts and the analysis of experimental data, we expect the students to understand the basic rules of how the nervous system operates. 

 

 
先修課程 
        Prerequisites
具備生物學基本概念即可!
  Basic biological concepts!
 
 
指定用書
        Text Books
♠ 
Eric R. Kandel, James H. Schwartz, Thomas M. Jessell, Steven A.

Siegelbaum and A. J. Hudspeth, Principles of Neural Science, 5th Ed., 2012 
 ♠  特別感謝書商麥格羅﹒希爾(McGraw-Hill)
  提供書籍圖片授權以俾進行影片製作,以下為此書籍之連結資訊!
 
 

參考資料
        References
Dale Purves, George J. Augustine, David Fitzpatrick and William C. 
  Hall,Neuroscience, 5th Ed., 2011
♠  Larry Squire, Darwin Berg, Floyd E. Bloom and Sascha du Lac,

Fundamental Neuroscience,4th Ed., 2012
John G. Nicholls, A. Robert Martin, Paul A. Fuchs and David A. Brown, 

From Neuron to Brain,5th Ed., 2011

 
   
 

 

授課大綱
        Syllabus
♠ Week 1 Organization of the nervous systems
♠ Week 2. Sensation and perception: touch and pain
♠ Week 3 Sensation and perception: vision I
 Week 4. Sensation and perception: vision II
 Week 5. Sensation and perception: audition,
olfaction, and gustation
♠ Week 6 Movement and action: peripheral mechanisms
♠ Week 7 Movement and action: central control
 Week 8 Movement and action: coordination and planning
   
   
 
瀏覽人次:26105
10802 自然科學
感覺與知覺
焦傳金 教授

跟著金導遊探索「感覺與知覺」,將以感覺系統搭配淺顯易懂的文字剖析您的感覺與知覺!這個問題,就讓清大的焦傳金教授回答你!想要抓住「感覺」,更要了解「知覺」的關係!

課程簡介
     Brief course description

     
「感覺與知覺」是一門神經科學的基礎課程,目的是將感覺系統的運作方式用淺顯易懂的方式介紹給大家。在這六周的課程中,每週將會有12的單元,每個單元約5分鐘影片,藉由回答許多與生活相關的有趣問題,各位將能學習到最新的腦科學新知,讓我們在與這個世界進行感官互動時,可以增添一份知識性。
課程目標 !
      This is a basic course in neuroscience. The goal is to introduce you to how the sensory system works in a clear and easy to understanding way. In this six-week course, there will be 12 units per week, each unit will have a 5 minutes video. By answering many interesting questions related to daily life, you can learn the latest brain science knowledge. Let us add a bit of knowledge while sensory interacting with the world. 
 
 
 
 

課程目標
     Course objectives

        
本課程中將以神經科學領域中的感官系統為基礎,循序漸進介紹人類的感覺與知覺,包括視覺、聽覺、觸覺、嗅覺、味覺等。這些感覺系統是人類接受外界訊息的媒介,除了影響我們的理性與思考,也會觸動我們的情緒與記憶,因此是一般社會大眾會有興趣的科普知識,也很容易引起多數人的關心。本課程的目標是以生動的文字、圖片及影片引發大眾的好奇心,並以淺顯方式將艱澀的神經科學知識轉化成一般人均可理解的切身經驗,在體驗與感受的過程中輕鬆學習科普常識,並將這些知識應用於日常生活中。
 In this course, based on the sensory system in the field of neuroscience, we will gradually introduce human sensations and perceptions including the sense of sight, hearing, touch, smell and taste. These sensory systems are the medium of human receiving external information which not only influence our rational and thinking, but also our emotions and memories. Therefore, it is a popular science knowledge that the general public will be interested in and can easily arouse most people’s concerns. The course objective is to trigger public curiosity with vivid text, pictures and videos. And transform difficult neuroscience knowledge into personal experience in a simple way that can be understood by everyone. Let us learn the popular and common science knowledge through experiences and feelings and apply this knowledge to daily life.

 
 
 
課程進度
     schedule
Week 1 視覺一(靈魂之窗)
Week 2 視覺二(影像腦中尋)
Week 3 聽覺(原音重現)
Week 4. 觸覺(肌膚之親)
Week 5 冷熱覺與痛覺(不可承受之輕)
Week 6 嗅覺與味覺(化學變化)

 
 
 
 

 

瀏覽人次:19772
10802 自然科學
應用數學入門〡遠距版
林秀豪 教授
Applied Mathematics is a two-semester course, emphasizing the basic mathematical training encountered in science and engineering. 
 
 
 
課程簡述
Brief course description 
Applied Mathematics is a two-semester course, emphasizing the basic mathematical training encountered in science and engineering. Facing the modern frontiers with brand-new challenges, the course contains the following key modules:
 It is important to maintain the balance between mathematical rigor and hands-on applications. Meanwhile, the last module (numerical methods) will be integrated into other modules to facilitate complementary usage of analytic and numeric techniques.

(1)

Complex Analysis
(2)

 Partial Derivative

(3) Linear Algebra
(4) Quantum Operators
(5) Fourier Transform
(6) Vector calculus
 
  
 
 
課程大綱
Syllabus 
Syllabus for Applied Mathematics (2020)
Applied Mathematics is a two-semester course, emphasizing the basic mathematical training encountered in science and engineering. Facing the modern frontiers with brand-new challenges, the course contains the following key modules: 
(1)  Preliminary
(2)  Partial differentiation
(3) Matrices and vector spaces
(4) Vector calculus
(5) Ordinary differential equations
(6) Integral transforms
(7)  Operators and special functions
(8) Partial differential equations
(9)  Probability and statistics
(10)  Numerical methods
It is important to maintain the balance between mathematical rigor and hands-on applications. Meanwhile, the last module (numerical methods) will be integrated nto other modules to facilitate complementary usage of analytic and numeric techniques.

 
 
Textbook
Mathematical Methods for physics and engineering (3rd edition)
  by Riley, Hobson and Bence
 
 
 In the first semester, we will cover the following key modules subjected
      to dynamical readjustments:
(1) Preliminary (4 lectures) – chap 1,2,3,4
(2)  Partial differentiation (2 lectures) – chap 5
(3) Matrices and vector spaces (8 lectures) – chap 7,8,9
(4) Vector calculus (6 lectures) – chap 10,11
 (5) ntegral transforms (4 lectures) – chap 12,13
 (6)  Ordinary differential equations (6 lectures) 
  – chap 14,15,16
   

 

 
 
 

 

瀏覽人次:112412
10802 自然科學
細胞神經科學
焦傳金 教授

腦科學為21世紀最重要的研究領域,而神經科學即是腦科學的基礎。本課程屬於「神經科學微學程」四個核心課程(細胞神經科學、系統神經科學、認知神經科學及計算神經科學)的其中之一。

課程概述
        Course Description

          腦科學為21世紀最重要的研究領域,而神經科學即是腦科學的基礎。本課程屬於「神經科學微學程」四個核心課程(細胞神經科學、系統神經科學、認知神經科學及計算神經科學)的其中之一。在本課程中,我們將介紹神經細胞的基本構造與功能、神經訊號的產生與傳遞、神經細胞間的溝通與塑性、神經細胞的發育與改變、神經系統的退化與再生。藉由重要觀念的解說與實驗數據的分析,本課程期望所有修習的學生都能對神經細胞的特性有充分的瞭解,做為探索腦功能的重要基礎。

          Brain science is the most important research area in 21st century and cellular neuroscience is the basis of brain science. This course is one of the core courses of neuroscience micro interdisciplinary program (which contains cellular neuroscience, systems neuroscience, cognitive neuroscience and computational neuroscience). In this course, we are going to introduce the basic structures and functions of nerve cells, the generations and transmissions of neural signals, the communication and neuroplasticity between nerve cells, development and changes of nerve cells, nerve degeneration and regeneration. With the explanation of important concepts and the analysis of experimental data, we expect the students to have a full understanding of nerve cells’ characteristics so as to become an important basis for exploring brain functions.



先修課程 
        Prerequisites 
具備生物學基本概念即可!
  Basic biological concepts!
 
 
 
指定用書
        Text Books
♠ 
Eric R. Kandel, James H. Schwartz, Thomas M. Jessell, Steven A.

Siegelbaum and A. J. Hudspeth, Principles of Neural Science, 5th Ed., 2012 
 ♠  特別感謝書商麥格羅﹒希爾(McGraw-Hill)
  提供書籍圖片授權以俾進行影片製作,以下為此書籍之連結資訊!
 
 

 
參考資料
        References
Dale Purves, George J. Augustine, David Fitzpatrick and William C. 
  Hall,Neuroscience, 5th Ed., 2011
♠  Larry Squire, Darwin Berg, Floyd E. Bloom and Sascha du Lac,

Fundamental Neuroscience,4th Ed., 2012
John G. Nicholls, A. Robert Martin, Paul A. Fuchs and David A. Brown, 


 
   
 
  

授課大綱
        Syllabus
♠ Week 1 Fundamental properties of neurons
♠ Week 2. Transmission of neural signals
♠ Week 3 Synaptic transmission: mechanisms
 Week 4. Synaptic transmission: neurotransmitters
 Week 5. Synaptic transmission: plasticity
♠ Week 6 Development of neurons
♠ Week 7 Development of synapses
 Week 8 Degeneration and regeneration of neurons
   
   
 

 

瀏覽人次:27755
10602 自然科學
幾何二
宋瓊珠 教授

This is an introductory course on the theory of curves and surfaces in the three dimensional Euclidean space. After developing the theory of curves, we will study the geometry of a surface from both intrinsic and extrinsic point of view. Topics include first and second fundamental forms, various notions of curvature, and the famous Gauss-Bonnet theorem.


課程簡述
Brief course description
This is an introductory course on the theory of curves and surfaces in the three dimensional Euclidean space. After developing the theory of curves, we will study the geometry of a surface from both intrinsic and extrinsic point of view. Topics include first and second fundamental forms, various notions of curvature, and the famous Gauss-Bonnet theorem.
 


課程說明
Course Description
This is an introductory course on the theory of curves and surfaces in the three dimensional Euclidean space. After developing the theory of curves, we will study the geometry of a surface from both intrinsic and extrinsic point of view. Topics include first and second fundamental forms, various notions of curvature, and the famous Gauss-Bonnet theorem. 
Prerequisites
 
Successful completion of Linear Algebra and Advanced Calculus 
 
 
 
指定用書
Text Books  
Differential geometry of curves and surfaces, by Manfredo P. Do 

Carmo. Prentice Hall.
 

  
參考書籍
 References  
Elementary Differential Geometry, 2nd edition, A. Pressley, Springer, 2010.
Elementary Differential Geometry, 2nd Edition, by Barrett O'Nell. 
   
   

教學方式
Teaching Method 
Lectures. 講授,演習,討論.  
  www.math.nthu.edu.tw/~cjsung/course/ug2018s.html

 

幾何二學生筆記

 

瀏覽人次:343027
10602 自然科學
高等微積分二
高淑蓉 教授
本課程以訓練嚴謹的邏輯推導、撰寫明確的證明、流利的口語表達為手段,追求如何思考、如何有效的學習為目標。This course is based on teaching you how to think logically, how to prove clearly and express yourself fluency.Also,how to think and how to learn effectively and the goals of this course.
 
 
課程簡述
Brief course description 
       本課程以訓練嚴謹的邏輯推導、撰寫明確的證明、流利的口語表達為手段,追求如何思考、如何有效的學習為目標。 
This course is based on teaching you how to think logically, how to prove clearly and 
express yourself fluency.Also,how to think and how to learn effectively and the goals of this course.
  
  
課程說明
 Course Description 
         本課程以訓練嚴謹的邏輯推導、撰寫明確的證明、流利的口語表達為手段,追求如何思考、如何有效的學習為目標。本課程內容探討歐幾里德空間的多變數函數之解析理論。本學期將介紹以下題材: 
    This course is based on teaching you how to think logically, how to prove clearly and express yourself fluency.Also,how to think and how to learn effectively and the goals of this course.The content of this course includes  the analysis of the multivariable functions in Euclidean space. The following topics are introduced in this semester:  
 1. Differentiable Mappings 
 2. The Inverse and Implicit Function Theorems and Related Topics 
 3. Integration 
 4. Fubini's Theorem and The Change of Variables Formula 
 5. Fourier Analysis 
 
  
指定用書
Text Books  
 J. E. Marsden and M. J. Hoffman, Elementary Classical Analysis,  

 second edition.
 
 
參考書籍
 References    
D. Widder, Advanced Calculus. 

T. Apostal, Advanced Calculus. 


教學方式 / 教學進度
 Teaching Method / Syllabus
 黑板授課/循序漸進 

 Teaching with Blackboard / Step by step

瀏覽人次:398787
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